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QB2-SDSingle-Use Precision Micropumps

The new single-use Quattroflow® Microdosing QB2-SD Pump operates entirely differently from the legacy line of Quattroflow products. Using the principle of positive displacement with a rotary action, the lightweight QB2-SD gently transfers fixed cavities of liquid of 25 μl with a maximum flow rate of 2.7 L/hr around a rotor from inlet to outlet. This provides high levels of accuracy without the need for additional sensors that are typically combined with peristaltic pumps. The pumps also generate a high vacuum capability and handle high viscosities.

The system allows easy and rapid changeovers since the single-use pumps simply click in and out of a motor drive, which is especially convenient when wearing full PPE.

The QB2-SD Microdosing Pump can be gamma irradiated up to 50 kGy with USP <88> Class VI certified materials, making it an ideal solution for handling biologics, including cells, proteins, mAbs, etc.

APPROVED BIOPHARMA CERTIFICATIONS

  • Particulate Testing (Sub-visible testing per USP 788)
  • Microbial Ingress
  • Endotoxin (USP 85)
  • Bioburden (ISO 11737-1)

Also available from PSG Biotech, Quattroflow is a plug-and-play drive device called Q-Drive-Alpha. The device is intuitively easy to use and can allow commercial use of the pumps in laboratories and similar environments.

Features & Benefits

  • Single-use – rapid changeovers with no cross-contamination
  • Lightweight, compact design – saving valuable space
  • Dosing with a minimum flow rate of 75 μl/s (at 1 rps) – for precision microdosing
  • Suitable for single transfer of cells with low shear – protecting product integrity
  • Self-priming, high vacuum capabilities – for positioning flexibility & higher product recovery
  • Bi-directional pumping – avoids drips during filling
  • Gamma compatible – up to 1 x 50kGy
  • USP <88> Class VI certified materials – ensuring biocompatibility

Technical Specifications

Using the principle of positive displacement with a rotary action, the QB2-SD has a 6 mm rotor that carries three cavities of fluid, each with a volume of 25 μl. This lightweight, in-line pump features hose-barbed connectors, making it easy to attach tubing to the inlet and outlet. A stepper or DC motor drives the pump at a maximum operating speed of 10 rps. The QB2-SD simply clicks in and out of the motor drive in seconds, making it quick and easy to swap fluids without cross-contamination. It is bi-directional, high-vacuum, and self-priming with a low dead volume.

Criteria Examples for QB2
Max. flow rate 45 ml/min (2.7 l/hr)
Resolution 25 μl
Operating Speed 1-10 rps
Baseline Accuracy ±6% 3SD
Maximum Pressure 0.2 bar
Max Vacuum -0.6 bar
Maximum Torque 100 mNm
Maximum Fluid Viscosity 500 cP
Operating Temperature 2-40°C
Dimensions (mm) 38W, 30L, 17H
Weight 6.4 g
Wetted Materials MBS, HDPE, SIL
Connector Sizing Hose barb for pump inlet and outlet. For use with 2 mm ID flexible tubing.
Longevity Up to 5L @ 5 rps (Up to 3L @10 rps)
Shelf Life 1 year
Longevity 1 x 50 kGy

Performance

Click on the images to enlarge.

FLOW V SPEED @ 3 PRESSURES

FLOW V SPEED @ 3 PRESSURES

FLOW (PER REV) V PRESSURE @ 4 SPEEDS

FLOW (PER REV) V PRESSURE @ 4 SPEEDS

FLOW REPEATABILITY & ACCURACY

FLOW REPEATABILITY & ACCURACY

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