Realizing the importance for pumping equipment that feature the design and performance characteristics required for chromatography systems, Quattroflow® offers quaternary (four-piston) diaphragm pump technology. Specifically designed for critical biopharma applications, Quattroflow pumps help ensure a reliable production and a safe end product thanks to a variety of features and benefits, including:
Pumping liquid through a chromatography column requires a relatively high pressure of 3 bar or more. This is caused by the back pressure from the chromatography column. Quattroflow pumps offer pressures up to 6 bar for multiple-use and up to 4 bar for single-use processes.
The flow rate of the pump is proportional to the motor speed, which simplifies the accurate control using PID control loops. In addition, the stability of the flow rate with changing discharge pressures is relatively low.
Using a powerful and accurate servo motor, Quattroflow downstream pumps offer a broad flow-range and allow stable operation even at lower flow rates. This is especially essential in gradient chromatography where the composition of the liquid phase is changed continuously, which is typically achieved with two or more pumps running in parallel.
Due to the consecutive actuation of four diaphragms, the pulsation is minimized to attain stable and repeatable flow conditions while achieving controlled conditions.